House, Locked In

Still mourning the death of his girlfriend, Wilson resigns from Princeton Plainsboro. House must determine if he is responsible for the death of his best friend's girlfriend. Later, Thirteen struggles to treat a patient objectively.

House and the team investigate a string of deaths centring around a single organ donor, then rush to save the only two surviving recipients. House auditions new best friends and uses a detective to spy on Wilson.

House and the team take on the case of a struggling artist with an undiagnosed illness that's distorting his perception and threatening his career. House continues to have a private investigator dig up dirt on everyone on his team.

After receiving word that his father has passed away, House is coerced into attending the funeral. The team tries to diagnose the illness of a woman who was in China searching for her birth mother.

Thirteen's date gets ill after a night of partying, and House takes on her case. Foreman confronts Thirteen about her self-destructive lifestyle, and private investigator Lucas is hot on Wilson's trail.

The team takes on the case of a sleepwalking patient experiencing unexplained blackouts. House discovers that Cuddy plans to adopt a baby due in two weeks.

House and the team treat an agoraphobic who adamantly refuses to leave his home and get treatment at the hospital. Chase and Cameron try to work through some kinks in their relationship, and House deals with an itch he can't scratch.

An emancipated minor working as a factory manager falls ill on the job. Foreman takes on a pediatric case that has him questioning whether he can function without House's oversight.

A man willing to kill or die for a diagnosis takes House, Thirteen and several patients hostage in Cuddy's office, where House tries to come up with the correct diagnosis.

House and the team treat a high-profile fitness trainer who collapses while shooting an infomercial; Thirteen participates in a clinical trial led by Foreman.

House and the team treat a teenager who collapsed during her high-school Christmas program. Foreman and Thirteen's relationship progresses, and Cuddy receives an unexpected gift.

House and the team try to diagnose a man's severe, chronic pain. Thirteen and Foreman explore their complicated relationship. Cuddy discovers that caring for her baby leaves her little time to run the hospital.

Cuddy gives some of her day-to-day responsibilities to Cameron. The team takes on the case of a teacher who collapsed after spitting up blood during a class.

While treating a former cancer researcher who gave up her career to pursue her happiness, House and his staff begin to question their own choices. Thirteen begins to show severe reactions to her experimental treatment.

A priest is admitted to the ER after he sees a bleeding Jesus hovering at his doorstep. House confronts Thirteen and Foreman about their relationship.

The team treats a teenager who doesn't know he has genetic mosaicism. Wilson and Cuddy think something is wrong with House when he starts acting friendly.

House and the team treat a patient who speaks his mind uncontrollably. House thinks Taub and Wilson are keeping something from him.

House sets out to disprove the allegations of a nursing home worker who feigns illness after being visited by the facility's pet cat, which has a reputation for visiting people who are about to die.

A man awakens in a New York hospital after a bicycle accident, unable to move or communicate. Injured and in the next bed, Dr. House insists he knows what is affecting the man and has him transferred to Princeton Plainsboro.

After caring for her dying husband for several months, a woman collapses and while his condition mysteriously improves, hers deteriorates.

Cameron asks House to accept the case of an environmental activist who collapsed at a protest with mysterious symptoms.

The team treats a deaf 14-year-old who collapses while competing in a wrestling match. House has trouble sleeping.

House and the team treat a ballerina whose lungs collapse during a performance. Meanwhile, House is desperate to find a cure for his insomnia.

House is intrigued by a patient whose left and right brains operate independently, creating two distinct personalities. as the season comes to a close.